coronavirus
- Thread starter eyephone
- Start date
There?s this malaria drug call Plaquenil (hydroxychloroquine) and it just might work against COVID19.
There are large trials in Korea, China, and France, and it is already part of the Belgian COVID treatment guidelines. It was tried 17 years ago during the SARS epidemic and was working, but when that epidemic died out people stopped looking at it.
Right now there is an ongoing 3000 patient study in France where people with close contact with COVID positive individuals like family members are being treated with Plaquenil or usual care (isolation, etc). The belief is that 75% of the people (or more) treated with Plaquenil will not convert to virus positivity, since in a small trial of 24 people infected with virus, 75% of them had no virus detectable one week after treatment. This follow-up study should announce in 2-3 weeks. Plaquenil sounds very promising, hope it really works. And best part is that it is very inexpensive.
https://www.forbes.com/sites/marybe...coronavirus--it-might-just-work/#c899305c4980
There are large trials in Korea, China, and France, and it is already part of the Belgian COVID treatment guidelines. It was tried 17 years ago during the SARS epidemic and was working, but when that epidemic died out people stopped looking at it.
Right now there is an ongoing 3000 patient study in France where people with close contact with COVID positive individuals like family members are being treated with Plaquenil or usual care (isolation, etc). The belief is that 75% of the people (or more) treated with Plaquenil will not convert to virus positivity, since in a small trial of 24 people infected with virus, 75% of them had no virus detectable one week after treatment. This follow-up study should announce in 2-3 weeks. Plaquenil sounds very promising, hope it really works. And best part is that it is very inexpensive.
https://www.forbes.com/sites/marybe...coronavirus--it-might-just-work/#c899305c4980
Innosint said:
CNBC article: Investor Bill Ackman urged President Donald Trump and corporate America in an impassioned plea on CNBC to shut down the country for 30 days to contain the fast-spreading coronavirus, calling it the only option to rescue the economy.
"What's scaring the American people and corporate America now is the gradual rollout," Ackman told Scott Wapner on "Halftime Report" on Wednesday. "We need to shut it down now. ... This is the only answer."
"America will end as we know it. I'm sorry to say so, unless we take this option," he said. Ackman added that if Trump saves the country from the coronavirus, he will get reelected in November.
Ackman urged U.S. companies to stop their buyback programs because "hell is coming." The biggest U.S. banks have already halted repurchasing stocks to put their capital to use helping consumers and businesses.
"The hotel industry and the restaurant industry will go bankrupt first, Boeing is on the brink, Boeing will not survive without a government bailout," Ackman said. "Capitalism does not work in an 18-month shutdown, capitalism can work in a 30-day shutdown."
https://www.cnbc.com/2020/03/18/bil...res-to-save-the-economy-shut-it-down-now.html
nosuchreality
Well-known member
Serious question for people. What are the public's WTF numbers for deaths from Covid-19?
What is the high number that makes people say didn't do enough?
What is the low number that makes people say, why did we do everything?
Yes, I realize the effort is to bend the curve, but how many deaths are curve bending success versus WTF?
What is the high number that makes people say didn't do enough?
What is the low number that makes people say, why did we do everything?
Yes, I realize the effort is to bend the curve, but how many deaths are curve bending success versus WTF?
CNBC: Tesla will take temperatures of Fremont factory employees and hand out masks, internal email says
https://www.cnbc.com/2020/03/19/tes...ll-have-temperatures-taken-and-get-masks.html
Please stop! We need to take your temperature.
10-4 We have a runner.
https://www.cnbc.com/2020/03/19/tes...ll-have-temperatures-taken-and-get-masks.html
Please stop! We need to take your temperature.
10-4 We have a runner.
morekaos
Well-known member
nosuchreality said:
If deaths do not spike over several thousand than the panic would have been for naught...if it stays in the low hundreds watch out for the rally and unraveling of the closures...if we exceed the H1N1 numbers, in the 12-17000 range then the panic was justified...I doubt we will.
Mety said:
If it is more lethal then why are you comparing to N1.
The number of people that get bitten by a rattle snake is lower than H1N1. But if you use the stats H1 is greater. But we all know without treatment a rattle snake bite is more deadlier.
That is where you and others argument is flawed and wrong.
eyephone said:
Haha. I think rattle snake bite without treatment is much more dangerous than Covid-19 and H1N1 combined.
It's not just the numbers we're comparing but the whole situation around. H1N1 killed half million people worldwide. To me, that's huge. But what I find interesting is that when that happened, no one was hoarding or being lockdown and stuff. Not much media attention was going on like how it's happening now.
We're not saying Covid-19 is fake. Just seeing how people react different in different times is interesting to me at least.
irvinehomeowner
Well-known member
lnc said:
I hope this isn't like Forsythia*.
*will someone get this?
nosuchreality
Well-known member
morekaos said:
You need to check your numbers. 17000 dead/ 60,000,000 infections = 0.03% death rate
Covid is 3% currently, 1% on happy path.
https://www.cdc.gov/flu/about/burden/2017-2018.htm
Or look at the bad 2017/2018 flu year with 61,000 dead and 45,000,000 infections. That is 0.1% mortality of infected.
It also hospitalized 800,000. Covid's happy path is still higher than that. And I'll a guess that those deaths tie up ventilators which is the sticky wicket.
Mety said:
But your not comparing apples to apples still.
I think your comparing a civic to a Ferarri.
Would you say a dog bite is lethal as a shark or mountain lion.
There are more reported dog bites than mountain lion and sharks. But the results are different. I rest my case.
morekaos
Well-known member
Death rates revised down...
Death rates of coronavirus may be HALF initial estimates by world health chiefs, promising study finds
International researchers compiled data on COVID-19 cases in Wuhan, China
They found that overall, the proportion of patients that died was 1.4 per cent
World Health Organization said in early March the death rate was 3.4 per cent
The preliminary findings come as the global death toll nears 10,000
The scientists suggested focusing on how to reduce the severity of the illness
https://www.dailymail.co.uk/news/article-8130815/Death-rates-coronavirus-HALF-initial-estimates-world-health-chiefs.html
Death rates of coronavirus may be HALF initial estimates by world health chiefs, promising study finds
International researchers compiled data on COVID-19 cases in Wuhan, China
They found that overall, the proportion of patients that died was 1.4 per cent
World Health Organization said in early March the death rate was 3.4 per cent
The preliminary findings come as the global death toll nears 10,000
The scientists suggested focusing on how to reduce the severity of the illness
https://www.dailymail.co.uk/news/article-8130815/Death-rates-coronavirus-HALF-initial-estimates-world-health-chiefs.html
nosuchreality said:
Unfortunately, I am already of the opinion that we didn?t do enough. I don?t think there is a low public number that would change my mind.
While I think Trump and the federal government handled this poorly, I don?t put all the blame on them. This is institutional and societal failure from top to bottom. We are just woefully unprepared for a pandemic as a country.
Comparing us to Taiwan (where I am from), they had federal funding and planning long before COVID-19. Predetermined measures were put in place very quickly in Taiwan while we have a deadlocked central government that can?t get anything meaningful done.
Locally, cities in Taiwan have been routinely drilling for emergencies and have large public awareness education campaigns for years. The only drills we have is active shooter drills in school. Public health education, social pressure, and even just insane amount of infographic for dummies posted everywhere about the benefits of social distancing has allow them to achieve massive societal buy-ins to bend the curve. Even if you don?t care about everyone wearing masks here, it?s nice to not have people irrationally hoarding toilet paper and supplies.
Taiwan currently have 75 cases and 1 death despite being so close to China. They did it without instituting a lockdown which is impressive. And will probably recover much quicker and suffer less economic destruction compared to us. We are stuck praying we don?t end up like Italy. We are very likely looking at months of disruption in our lives and will face a deep recession.
Sorry didn?t completely answer your question but I will be happy if this ends with 0 deaths among my friends/family/coworkers/TI members
irvinehomeowner said:
Plaquenil is not approved by FDA for COVID19 yet but Trump is pressuring FDA to approved it.
Patient only need to take one 200mg pill daily for 3-5 days and each pill only cost $1-2.
All the study so far about Plaquenil is very promising, hope it works.
I mostly agree, except I do think Trump has a lot of blame to shoulder.
https://foreignpolicy.com/2020/01/3...ited-states-public-health-emergency-response/
Like ceasing to wear a helmt because you've never needed one before.
https://foreignpolicy.com/2020/01/3...ited-states-public-health-emergency-response/
Like ceasing to wear a helmt because you've never needed one before.